Sheldon's eccentricities don't always gel with his family. Throughout the show's run, he's frequently gotten on the wrong side of his parents and siblings, but his grandmother has taken a different approach. Annie Potts continued to explain how she and Sheldon forged a significant bond, "Meemaw makes no bones about the fact that Sheldon is her favourite grandchild. She likes the others, but she hardly has the time of day for them." The other kids in the Cooper household have their fair share of problems, but Sheldon always stood out. It makes sense Meemaw would take extra special care to ensure he was looked after.
Potts elaborated, "She senses Sheldon is unusual and that he needs her because his parents are terrified of him. She's not afraid of him – and she can teach him things he doesn't know, like poker. Very useful things!" Fans knew from watching "The Big Bang Theory" that Sheldon always had a hard time connecting with his father, and it's easy to see why on "Young Sheldon." The two are practically from different worlds, but Meemaw makes the extra effort to see things from Sheldon's point of view, giving him a role model he can confide in.
It may sound harsh for a grandmother to have a favorite grandchild, but for the Coopers, it makes sense. Sheldon needs Meemaw more than the other kids, and she's more than happy to see things from his unique perspective.
