In the episode "Find Me," Daryl reveals the painful truth about what happened with Leah (Lynn Collins), a woman he had a relationship within the years following Rick's disappearance. Like Rick, Leah also vanished from Daryl's life, and he seems to be harboring guilt over how he handled their relationship. It's when Carol tries to comfort him about the situation that he lashes out at her. While his accusations don't exactly come out of nowhere, at that moment, Daryl was likely looking for someone to project his feelings of heartache and regret onto other than himself.

Carol was rightfully hurt by Daryl's harsh words toward her. However, their fight also happened at a time when she was already feeling extremely vulnerable. As we've seen throughout the season 10C episodes, especially "Diverged," in a post-Whisperer War Alexandria, Carol is racked with insecurities about the state of their community and her role in it. "Find Me" saw Carol trying hard to get Daryl to talk with her about this when it was clear that he wanted to be left alone. At a time when Carol was craving connection, Daryl was needing space. During an emotionally charged moment in both of their lives, that dissonance led to conflict.

There is, however, one simple reason to have hope that they will find a way to move past this tough time: the foundation of Daryl and Carol's relationship is strong. It has been forged in the fires of the apocalypse and one conflict isn't likely to tear it down. Season 10C may have left them more distant from each other than ever, but it's entirely possible we'll see them riding together as friends again before the end of The Walking Dead's final season.