The Professor is by no means the strongest antagonist Geralt has to carve his way through in the games, but the assassin is nevertheless a formidable challenge whom the Witcher faces more than once. He's a condescending, snide man who isn't afraid to rely on underhanded tactics like wrist-mounted crossbows and powerful protective spells. He also shows very little fear while fighting Geralt, and isn't shy to lecture the protagonist about his less-than-pleasant views on the subject of Witchers.
Apart from being a brief nod at the people familiar with the first "The Witcher" game, the assassin's presence in the Netflix show is also a fun meta-joke of sorts. Because the Professor is one of the two first major bad guys Geralt encounters in his very first game (the other being Azar Javed), he can be viewed as something of a starter villain. Here, he's pitted against a considerably stronger and more experienced Geralt with a mission — and the power imbalance between the two is not unlike what would happen if a video game character returned to the first area of a game after maxing all his stats. Thanks for dropping by, Professor!