During the Ninja Turtles' climactic fight with the rampaging Super Duper Fly, the media, unfortunately, misreports that they are in cahoots with the villainous monster, even aiding him in the destruction of New York City. That is, until April O'Neil is able to infiltrate a live news broadcast in the middle of the big kaiju fight and explain to the citizens of the city (after overcoming her stage fright) that the Turtles are actually fighting to the death to protect the people.
Afterward, when Super Duper Fly is about to crush the Turtles "like pistachios" and things are at their most dire, the humans of New York rise up and help save them from certain doom, giving them the leg up to escape and finally defeat the giant fly monster for good. After saving the city, the Ninja Turtles then become instant celebrities, signing babies, getting asked for selfies, etc.
In this way, the ending disproves both Superfly and Splinter's views on humanity. Namely, while discrimination does indeed exist (such as Splinter being attacked in the past, as well as the evil TCRI (Techno Cosmic Research Institute) corporation that wanted to extract the ooze or "milk" the Turtles), the Turtles learn that humans can also be helpful, kind, and supportive. By defending the Turtles, the people of New York proved to Splinter that they were indeed worth saving. At the very end, the Turtles even get accepted to go to high school like they always wanted to.
