Majel Barrett remained part of the "Star Trek" galaxy longer than most. It doesn't matter if you consider yourself a hardcore fan or just someone with a passing interest — in most likelihood if you have seen a single movie or episode of a "Star Trek" TV series, then you have seen (or at least heard) Majel Barrett, who also happened to be married to "Trek" creator Gene Roddenberry from 1969 until his death in 1991.
If you're hearing the voice of a Federation computer speak back to the heroes on "TNG" or any of the late '80s to early '00s series, in most likelihood you're hearing Barrett. She did the computer voice work on "TNG," "DS9," and "Voyager." That includes the "TNG" era movies "Generations," "First Contact," and "Nemesis."
On the original series, Barrett appeared both as Number One in the pilot episode of "Star Trek" and later as Nurse Chapel. Nurse Chapel would eventually become Doctor Chapel, and show up in both "Star Trek: The Motion Picture" and "Star Trek IV." On "TNG" and "DS9," Barrett had the fan-favorite recurring role of Lwaxana Troi — Deanna Troi's overbearing mother and regular pain-in-the-neck to Captain Picard.
Interviewed for Star Trek: The Next Generation – The Official Magazine Series in 1988 (via StarTrek.com), Barrett showed little interest in ever reprising the role of Chapel. But she added that Lwaxana Troi was a "much more fun character" than Chapel and that she could "play her forever."
