Although official plot details for "Love 101" Season 2 haven't yet been revealed, it's likely the show will pick up where Season 1 left off. The Season 1 finale left many ongoing storylines unresolved, so there are lots of directions this could go.
The biggest question is, how will the revelation that Ms. Burcu's new relationship with the basketball coach Kemal was orchestrated by the students affect their relationship going forward? Ms. Burcu has always advocated for a more lenient approach towards the core five troublemakers. But realizing that the students manipulated her into love might fundamentally change their dynamic. Most likely, Season 2 will deal with the students and Ms. Burcu trying to regain each other's trust.
Then there are the consequences for the core five's defiance. In the finale, rather than apologize for their misbehavior, the students defied the school administration for their strict disciplinary system. The threat of expulsion has always hovered over the students, and it looks like Season 2 might see that become more likely.
There are also big questions the show has teased but so far left unanswered. In flash-forwards, with older versions of Isik and Eda, the show has implied that something tragic might have befallen the group, which led to them all splitting up some time after high school. It's possible Season 2 will shed more light on what happened.