More likely than not, "Komi Can't Communicate" will be a rather faithful adaptation of its source material, focusing on Komi's social development as she strives towards her goal of making 100 authentic friends. As a "slice of life" anime, the show will likely forgo the action-oriented narratives that define other popular anime (such as "Dragon Ball" or "Naruto"), instead depicting the lives and struggles of its characters in a mundane setting.
Still, Komi's long term goal establishes that the show will have a sense of progression and conflict, as Komi works to break through her social barriers. How she and her allies accomplish this task will no doubt act as the show's meat and potatoes.
However, it's unclear how far into the manga the series will take its adaptation. Komi will be miles away from her goal of making 100 friends, and it's doubtful that she would ever attain this benchmark in the time it takes for the anime to complete its debut season. Manga readers might already be leagues ahead of where the anime will conclude. Even so, newcomers to the series will get a kick out of witnessing Komi and her friends do their best to cure her social anxieties.