Itachi Uchiha's Mangekyou Sharingan puts him near the top of the most powerful shinobi in "Naruto," and his elevated Kekkei Genkai allows him to call upon the powers of Izanagi's children against any opponent.
From his right eye, Itachi can activate Amaterasu, creating an endlessly burning black flame in any location. Although the Amaterasu present in Shinto doesn't boast a black fire, she is the sun goddess, making her one of the religion's most important deities. It's clear Masashi Kishimoto wanted to showcase the strength of Amaterasu in "Naruto," using the goddess's name for a fire strong enough to burn through anything. From his left eye, Itachi calls upon the Tsukuyomi. This genjutsu creates a physically and mentally harmful illusion in which he controls space and time, allowing Itachi to torture victims endlessly while only seconds of actual time has passed. Little is known of Shinto's Tsukuyomi, but Kishimoto giving Itachi the powers of endless nights seems fitting for the moon god.
Using both eyes, Itachi brings the Susanoo forward, creating a massive chakra-based avatar. The strongest Mangekyou Sharingan ability, the Susanoo takes direct inspiration from Shinto, even wielding god-like weapons during battle. During Itachi's final battle with Sasuke, he uses the Susanoo to kill Orochimaru, who appears in a serpent-like form. While fitting for the series, this is another direct reference to Shinto and the legend of Susanoo, who famously killed a monstrous serpent.
