Both "Big Mouth" and "Human Resources" have historically made hilarious use of celebrity voice actors, bringing them in for an episode or two in memorable guest-starring roles. Season 2 of the latter will be no exception, already boasting a star-studded roster in early promotional materials.

Most noticeable among the crowd of newcomers is Academy-award nominee Florence Pugh, who most recently lent her voice to the critically acclaimed animated film "Puss in Boots: The Last Wish." Multihyphenate entertainer Miley Cyrus is also set to voice a character in Season 2, possibly one based on herself. Also to be heard are Eugene Levy ("Schitt's Creek"), Sam Richardson ("Velma"), Niecy Nash-Betts ("Monster: The Jeffery Dahmer Story"), and Isabella Rossellini ("Marcel The Shell with Shoes On"). Finally, character actor Jason Mantzoukas, who voices Jay Bilzerian in "Big Mouth," will guest star.

Aidy Bryant, Randall Park, Keke Palmer, David Thewlis, Brandon Kyle Goodman, Maya Rudolph, and Nick Kroll are all set to return as series regulars, voicing the characters they originated in the first season. A fair amount of previous guest stars could also be returning, including Hugh Jackman, Pamela Adlon, Rosie Perez, Henry Winkler, Thandiwe Newton, Jemaine Clement, Maria Bamford, Bobby Cannavale, and Cole Escola.