In "Hulk" #4, from Marvel Comics, Bruce Banner and Charlie's pitstop leads to them being split up. As Charlie is haunted by her deceased younger brother, Banner is approached by Man-Thing, with the creature towering over his human form. However, as Bruce tries to reason with him and inform him about the Eldest and the undead monsters that have attacked him, Man-Thing grabs Banner and absorbs him into his body.

The Hulk doesn't take kindly to the fiery connection with Man-Thing, and the Jade Giant's arm emerges from the body of the monster who swallowed him. The Hulk rips apart Man-Thing from inside his body, leaving him in pieces. However, when the dust settles, Man-Thing's human form, Ted Sallis, appears and tells the former Avenger that he's inside the Nexus of All Realities with him. Sallis reveals he needed to talk with Hulk and that his physical form wasn't capable of doing so with as much clarity as he would have inside the Nexus.

Man-Thing shares that the Nexus of All Realities is in danger from the Eldest, who is too strong for him to deal with alone. Sallis adds she's older than anything he's ever encountered before. While Hulk and Man-Thing have had their fair share of tussles in the past, the two powerful monsters are about to work together to stop the Eldest from freeing the Mother of Horrors and prevent the destruction of the Nexus of All Realities. So the pair will need to put aside their differences to take on a common enemy who's much more powerful than either of them could handle alone.