Although Camilla Luddington believes that the show's imperfect characters are what attracts viewers, her character has gotten the short end of the stick on more than one occasion. Jo Wilson had a rocky start in life and used all the resources at her disposal to make it through medical school. Jo originally came to Seattle to escape her abusive ex-husband, only to face him again just when she'd settled in. She fell in love with Alex, only for him to leave her for Izzie Stevens (Katherine Heigl). Jo is a character who struggles to forge close relationships because of her history and deep-seated trust issues, though that's not the case for the actress who plays her. In an interview with Elle, Luddington revealed that she still keeps in touch with her former co-star, Jessica Capshaw.

"I think of Jessica Capshaw as my American sister. I adore her so much, we speak all the time, probably way too much," the British actor explained to the outlet. "But to be honest, I've grown close to everybody, too."

Although Jo and Arizona weren't particularly close when both characters were leading players on "Grey's Anatomy," it makes sense that Luddington and Capshaw got to know each other during the long hours spent on set. Even though Capshaw isn't on the show anymore, it's nice to see that the cast members are forging real-life friendships behind the scenes.